Clomid 50

Dosage:
24 X 50MG Tablets
Manufacturer:
Anfarm Greece Effective dosage:
25-100 mcg/day
Additional comments:
Drug Class: Synthetic thyroid hormone.
Comments: Significant suppression of Thyroid function during use.
Clomid detailed information:
Clomid is the anti-estrogen of choice for improving recovery of natural
testosterone production after a cycle, improving testosterone
production of endurance athletes, and is also effective in reducing
risk of gynecomastia during a cycle employing aromatizable steroids.
While it has been claimed that Clomid "stimulates" production of LH and
therefore of testosterone, in fact Clomid's activity is achieved not by
stimulation of the hypothalamus and pituitary, but by blocking their
inhibition by estrogen.
Clomid is a mixed estrogen agonist/antagonist (activator/blocker)
which, when bound to the estrogen receptor, puts it in a somewhat
different conformation (shape) than does estradiol. The estrogen
receptor requires binding of an estrogen or drug at its binding site
and also the binding of any of several cofactors at different sites.
Without the binding of the cofactor, the estrogen receptor is inactive.
Different tissues use different cofactors. Some of these cofactors are
able to bind to the estrogen receptor/Clomid complex, but others are
blocked due to the change in shape. The result is that in some tissues
Clomid acts as an antagonist - the cofactor used in that tissue cannot
bind and so the receptor remains inactive - and in others Clomid acts
as an agonist (activator), because the cofactors used in that tissue
are able to bind.
Clomid is an effective antagonist in the hypothalamus and in breast
tissue. It is an effective agonist in bone tissue, and for improving
blood cholesterol.
Clomid also has the property of reducing the adverse effect of
exercise-induced damage of muscle tissue. This is very significant for
endurance athletes but is not very significant, if at all significant,
with reasonable weight training. Clomid does not perceptibly affect
gains of the weight trainer either favorably or adversely in my
experience.
The drug seems to have estrogenic effects on mood, which can be
beneficial (improving relationships with women by improving empathy) or
can yield depression or PMS-like symptoms, but for most users there is
no significant effect either way.
The claim that duration of intake should not exceed 10-14 days is
incorrect. Clinical studies with male patients have been for periods of
a year or longer. This error probably originates from the fact that,
for use in women, due to the menstrual cycle there would obviously be
no point in trying to stimulate ovulation all four weeks of the month.
Thus, use in women is limited to 10-14 days. That limitation is not
because of toxicity.
Clomid is in fact useful throughout a cycle if aromatizable drugs are
being used.. We do think however that to be conservative, one should
use it no more than 2/3 of the time throughout the year or a little
less.